Psoriasis

What is Psoriasis?

Psoriasis is a chronic autoimmune skin condition that causes the rapid buildup of skin cells, leading to scaling, inflammation, and redness. It can affect various parts of the body, including the scalp, elbows, knees, and lower back, and may range from mild to severe. Psoriasis often occurs in cycles, with flare-ups followed by periods of remission.

Symptoms of Psoriasis May Include:

• Red, inflamed patches covered with silvery-white scales
• Dry, cracked skin that may bleed
• Itching, burning, or soreness in affected areas
• Thickened or ridged nails (nail psoriasis)
• Temporary hair loss if the scalp is affected

Facts About Psoriasis

• Psoriasis affects about 7.5 million Americans, with most cases diagnosed in early adulthood.
• It is not contagious, but it is linked to immune system dysfunction and may be associated with other health conditions, such as obesity and heart disease.
• Stress, infections, cold weather, and certain medications can trigger psoriasis flare-ups.

Who is at Risk for Psoriasis?

Risk factors for psoriasis may include: 

• Genetics: A family history of psoriasis increases the risk of developing the condition.
• Age: Psoriasis can develop at any age, but it most commonly appears in young adults.
• Sex: Psoriasis affects both men and women equally.
• Race or Ethnicity: It occurs more frequently in Caucasian populations but can affect people of all backgrounds.
• Other Risk Factors: Stress, smoking, alcohol use, and obesity may worsen symptoms.

How Many Americans Have Psoriasis?

Approximately 2-3% of the U.S. population lives with psoriasis, with varying levels of severity.

Diagnosis & Management

Psoriasis is typically diagnosed through a physical exam and patient history. In some cases, a skin biopsy may be performed to confirm the diagnosis.

Treatment Options for Psoriasis

Medical and Pharmaceutical Treatments 

• Topical Treatments: Corticosteroids, vitamin D analogs, and salicylic acid are commonly prescribed to manage inflammation and scaling.
• Systemic Medications: In more severe cases, immunosuppressants or biologics may be used.
• Phototherapy: Light therapy can help slow skin cell growth and reduce inflammation.

Lifestyle Interventions 

• Moisturizing Routine: Daily use of thick moisturizers helps reduce dryness and scaling.
• Stress Management: Managing stress is important, as it can trigger flare-ups.
• Avoiding Triggers: Identifying and avoiding triggers such as smoking, alcohol, and cold weather can help manage symptoms.

Have you been diagnosed with psoriasis?

At Clinical Investigation Specialists, Inc. (CIS Research), we are committed to advancing dermatological care through innovative clinical research. You may be eligible for a clinical trial exploring new treatment options for psoriasis. For more information on currently enrolling studies, click here.

Sources & Further Reading

• National Psoriasis Foundation
• Mayo Clinic: Psoriasis

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