What is Gastroesophageal Reflux Disease (GERD)?

Gastroesophageal Reflux Disease (GERD) is a chronic condition where stomach acid frequently flows back into the esophagus, causing irritation and symptoms such as heartburn. If left untreated, GERD can lead to more serious health issues, including esophageal damage.

Symptoms of GERD May Include:

• Heartburn or a burning sensation in the chest
• Regurgitation of food or sour liquid
• Difficulty swallowing
• Chronic cough or hoarseness
• Sore throat or feeling of a lump in the throat

Facts About GERD

• GERD affects up to 20% of the American population.
• It can develop at any age but is more common in adults and can become more severe with age.

Who is at Risk for GERD?

Risk factors for GERD may include:

• Genetics: A family history of GERD or other gastrointestinal conditions increases the risk.
• Sex: Both men and women can develop GERD, but women are more likely to experience symptoms during pregnancy.
• Age: GERD can develop at any age, but risk increases with age.
• Other Risk Factors: Obesity, smoking, pregnancy, and certain medications can exacerbate GERD symptoms.

How Many Americans Have GERD?

Approximately 20% of Americans experience GERD symptoms on a weekly basis, with many more having occasional symptoms.

Diagnosis & Management

GERD is diagnosed through a combination of symptom assessment, endoscopy, and sometimes pH monitoring. Effective management often involves lifestyle changes, medications, and sometimes surgery.

Treatment Options for GERD

Medical and Pharmaceutical Treatments

• Medications: Antacids, H2 receptor antagonists, and proton pump inhibitors are commonly used to manage GERD symptoms.
• Surgery: In severe cases, surgical options such as fundoplication may be considered to improve symptoms.

Lifestyle Interventions

• Dietary Changes: Avoiding trigger foods and eating smaller, more frequent meals can help manage symptoms.
• Weight Management: Losing excess weight can reduce GERD symptoms significantly.
• Sleep Positioning: Elevating the head of the bed can help prevent acid reflux during sleep.

Have you been diagnosed with GERD?

At Clinical Investigation Specialists, Inc. (CIS Research), our mission is to advance medical care for adults through innovative clinical research. You may be an eligible candidate for a clinical trial researching treatment options. For more information on currently enrolling clinical trials, click here.

Resources

• Acid Reflux/GERD | ACG (gi.org)
• Mayo Clinic: Gastroesophageal Reflux Disease (GERD)

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